Smells
If one is willing to invest the time and money, an entire neighborhood can be stunk up rather easily. Typically, a group of dedicated volunteers will stealthily place stench-inducing materials in every nook and cranny they see within a 2 city block radius. Make sure to then place paper flyers everywhere defiantly declaring your actions with a picture of your victim posed aggressively.

Sounds
A successful sound prank usually relies on your recording skills and a dependable microphone of some sort. The main focus should be getting your victim to speak obscenities, vile statements or accusations against the neighbors. After recording the statements, edit to make the victim sound really bad and burn a CD. Obtain a bullhorn and play the CD through it while slowly driving around through the immediate neighborhood.

Bugs/Pests
For the next door neighbors, nothing irritates them more than breeding millions of bugs on your victim’s property. Wieners and honey are especially effective at drawing many different types of hungry beasts.

Accidental Damage
About 30 feet of strong cord and a vehicle is all you need to really irritate your victim’s neighbor. On a day when you know your victim will be hurrying somewhere in the morning make sure to arrive in their driveway about 4:30am and tie one end of a long, heavy duty cord to your victim's vehicle. Tie the other end to a neighbor’s hedge, mailbox or small tree. Then hide the cord so that your victim hurriedly pulls out and hits the accelerator hopefully, taking the neighbor’s landscaping with them.